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flavoxate hcl 100 mg tablet

In stock Manufacturer PERRIGO CO. 00574011501
$1.05 / Tablet

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Flavoxate hydrochloride is used as an antispasmodic to provide symptomatic relief of dysuria, urgency, nocturia, suprapubic pain, frequency, and incontinence that may occur in patients with cystitis, prostatitis, urethritis, urethrocystitis, or urethrotrigonitis. Flavoxate therapy is not indicated as definitive treatment of these conditions but is compatible with drugs used for the treatment of urinary tract infections. Flavoxate has not been shown to be more effective in the treatment of these conditions than antimuscarinic agents.

Dosage and Administration


Flavoxate hydrochloride is administered orally.


The usual dosage of flavoxate hydrochloride for patients older than 12 years of age is 100-200 mg 3 or 4 times daily. Dosage may be reduced as symptoms improve.


Adverse Effects

Adverse effects of flavoxate hydrochloride include nausea and vomiting, dry mouth and throat, nervousness, vertigo, headache, drowsiness, blurred vision, increased ocular tension, disturbance in ocular accommodation, urticaria and other dermatoses, mental confusion (especially in geriatric patients), dysuria, tachycardia and palpitation, hyperpyrexia, and eosinophilia. Rarely, abdominal pain and difficulty in concentration may occur. Constipation has been reported in patients receiving 800 mg to 1.2 g of flavoxate hydrochloride daily. One case of leukopenia which was reversible following discontinuance of the drug has been reported.

Precautions and Contraindications

Because of possible drowsiness, vertigo, and ocular disturbances, flavoxate should be administered with caution to patients performing hazardous tasks requiring mental alertness or physical coordination. Flavoxate hydrochloride should also be administered with caution to patients with suspected glaucoma. The drug is contraindicated in patients with pyloric or duodenal obstruction, obstructive intestinal lesions or ileus, achalasia, GI hemorrhage, or obstructive uropathies of the lower urinary tract.

Pediatric Precautions

Safety and efficacy of flavoxate hydrochloride in children younger than 12 years of age have not been established.

Mutagenicity and Carcinogenicity

Studies to determine the mutagenic and carcinogenic potentials of flavoxate hydrochloride have not been performed.

Pregnancy, Fertility, and Lactation


There are no well-controlled studies using flavoxate hydrochloride in pregnant women, and the drug should be used during pregnancy only when clearly needed.


Reproduction studies in rats and rabbits using flavoxate hydrochloride doses up to 34 times the human dose have not revealed evidence of harm to the fetus or impaired fertility.


Since it is not known whether flavoxate hydrochloride is distributed into milk, the drug should be used with caution in nursing women.


Based on animal studies, flavoxate hydrochloride appears to be well absorbed from the GI tract. In rats, peak plasma flavoxate concentrations were achieved approximately 2 hours following oral administration of the drug. In one study in healthy males, the onset of action was 55 minutes and the peak effect occurred at 112 minutes. It is not known whether the drug is distributed into milk. The manufacturer reports that 57% of a dose of flavoxate hydrochloride is excreted in urine within 24 hours after oral administration. It is not known whether the drug is dialyzable.

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