Gentamicin is used topically in the treatment of superficial infections of the skin caused by susceptible bacteria. However, substantial evidence of effectiveness is lacking and some experts question the use of topical antibiotics in general. Minor skin infections and wounds usually heal without treatment, and systemic anti-infective therapy is required for the treatment of serious or extensive skin infections. In addition, indiscriminate use of topical gentamicin may result in the emergence of organisms resistant to the drug and other aminoglycosides.
For systemic uses of gentamicin, see 8:12.02. For use of gentamicin in infections of the eye, see 52:04.04.