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How does an FSA work?
Flexible Spending Accounts will reimburse you for incurred expenses during your FSA plan year (period of coverage).
“Incurred” refers to expenses that happen after a service or product is provided – not when you are billed or pay for the service.You cannot be reimbursed in advance for any services.
Because FSA funds are available to you on the first day of your plan year, you must be able to receive full reimbursement for your contribution.
So, if you opted in for $1,200 a year for your FSA, you could use that amount on the first day (if you wanted to).
You can submit for FSA reimbursement in two ways:
1. Your FSA Administrator might provide you with an FSA Debit Card to use toward FSA eligible expenses.
You’ll be able to use the card at approved stores or pharmacies (we accept FSA Debit Cards and all major credit cards at FSAstore.com!)
By using the FSA debit card, your expenses are auto-adjudicated (electronically approved or disapproved) from the card and you may not need to submit additional receipts to your FSA Administrator.
Some FSA Administrators could still require a receipt to substantiate a claim. Check with your FSA Administrator about reimbursement procedures for your plan.The FSA Debit Card would not be charged if something is not considered FSA eligible under your plan.
2. You’ll have to typically submit a reimbursement claims form with:
- your personal details,
- product/service details(provider information)
- amount owed
- date of service provided.
FSAstore.com can provide you with an itemized receipt after you make your order to submit to your FSA Administrator for FSA reimbursement.
Collagenase is used to promote debridement of necrotic tissue in the treatment of severe burns and dermal ulcers including decubitus ulcers.
When applied daily to experimental third-degree burns in animals, collagenase ointment or powder produced total separation of the burn eschar within 7 days. Similar burns treated with trypsin or fibrinolysin and desoxyribonuclease (no longer commercially available in the US) required 14 days of enzyme application before eschar separation occurred. In one comparative study in patients 5-60 years of age with partial-thickness burn wounds, therapy with collagenase ointment and Polysporin powder (polymyxin B sulfate and bacitracin zinc) was at least as effective (as measured by the time to a clean wound bed and the time to healing [complete epithelialization]) as silver sulfadiazine 1% cream. In one group of patients, debridement of decubiti occurred within 10 days when daily application of collagenase ointment was used. Another group of patients with stasis ulcers of the lower extremities received topical application of collagenase ointment once or twice daily; debridement occurred within 6 days in about half of the patients.
For other uses of collagenase, see Collagenase Clostridium Histolyticum 44.00.
Dosage and Administration
Collagenase is applied topically as an ointment once daily. If the dressing becomes soiled (e.g., due to incontinence), collagenase may be applied more frequently. Strict aseptic conditions should be maintained.
If the lesion to be treated with collagenase has been exposed to detergents or heavy metal ions incompatible with collagenase, the site should be carefully cleansed by repeated washings with 0.9% sodium chloride solution. Prior to each collagenase application, the lesion should be gently cleansed with a gauze pad saturated with 0.9% sodium chloride solution or another cleaning solution that is compatible with collagenase ointment to remove necrotic material. As much loosened detritus should be removed as can be done readily with forceps and scissors. Thick eschar may be cross-hatched with a #10 scalpel blade.
When infection is present, a topical antibiotic can be used concomitantly. An appropriate antibiotic compatible with collagenase may be applied to the lesion as a powder prior to application of collagenase. If the infection does not respond to this combined therapy, collagenase should be discontinued until the infection has resolved.
Collagenase ointment may be applied directly to the wound or to a sterile gauze pad which is then applied to the wound and properly secured. Caution should be used to restrict application of the enzyme ointment to the lesion, avoiding application to healthy surrounding skin. A sterile gauze pad should be placed over the wound.
Application of collagenase should be discontinued when debridement of necrotic tissue is well established.
Pain and burning may occur at the site of collagenase application. Slight erythema may develop in surrounding tissue, especially if the ointment is not confined to the lesion being treated. The ointment should be applied carefully within the affected area.
A systemic hypersensitivity reaction to collagenase has been reported following prolonged use (more than one year) of collagenase in conjunction with cortisone.
Precautions and Contraindications
Because of the theoretical possibility that debridement may increase the risk of bacteremia, debilitated patients receiving treatment with collagenase should be observed for evidence of systemic bacterial infection.
Collagenase probably should not be introduced into major body cavities, such as pleural or peritoneal cavities. Collagenase is contraindicated in patients who show local or systemic hypersensitivity to the enzyme.
Although systemic or local reactions attributable to overdosage have not been observed in collagenase-treated patients, if inactivation of collagenase is deemed necessary, the area may be washed with povidone iodine.
Safety and efficacy of collagenase ointment in pediatric patients have not been established.